Author

Mohammed A. Akeel

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Open access Sep 2026

Liposomal Morin Attenuates DMH-Associated Colonic Oxidative Stress, Inflammation, and Apoptosis/Autophagy-Related Dysregulation in Rats

In DMH-exposed rats, MOR-Lips were associated with more favorable redox, inflammatory, proliferative, apoptosis-related, autophagy-related, and histopathological profiles than free MOR, which supports further investigation of MOR-Lips as a formulation strategy for improving the biological activity of morin.

M. Akeel, E. Elmorsy, F. Alshammari et al. · Pharmaceuticals · 0 citations

Open access Aug 2026

Hesperetin-Loaded PLGA Nanoparticles Ameliorate Cisplatin-Induced Oxidative Stress and Testicular Dysfunction in Rats: Association with NRF2/HO-1, NF-κB, and ACSL4/GPX4/SLC7A11 Signaling Modulation

HES and HES-PLGA-NPs were associated with multi-mechanistic protection against cisplatin-induced oxidative, inflammatory, apoptotic, and ferroptosis-associated damage in the testes, and may represent a promising nanoantioxidant candidate warranting further investigation for preserving male reproductive function during...

Mohammed A. Akeel, E. Elmorsy, Aly A. M. Shaalan et al. · Antioxidants · 0 citations