Summary Background Tetanus is a life-threatening, vaccine-preventable disease. Its incidence decreased substantially following global initiatives such as the Expanded Programme on Immunization (EPI) and Maternal and Neonatal Tetanus Elimination (MNTE). Despite these efforts, tetanus elimination has not been achieved, a...
D. Areda, Hyunjee Kim, Ji-Seung Kang et al.· EClinicalMedicine· 0 citations
Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC) remains a clinically challenging malignancy, particularly in recurrent or metastatic disease where durable responses to chemoradiotherapy and immune checkpoint blockade are limited. The viral aetiology of NPC provides a strong biological rationale for i...
N. Allehyani, Mohammed Alissa, Abdullah Alghamdi et al.· Reviews in Medical Virology· 0 citations
Cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae increasingly limit therapeutic options, necessitating novel antimicrobial strategies. This study investigated the antibacterial and immunomodulatory potential of a bioactive Streptomyces isolate (SGM-12) and its silver nanoparticle (AgNP) formulations u...
Mohammed Alissa· Microbial Pathogenesis· 0 citations
Oncoviruses are responsible for a substantial fraction of human cancers and have emerged as critical modulators of host cellular pathways that also govern ageing. The convergence of viral oncogenesis, ageing, and cancer reflects shared molecular mechanisms, including genomic instability, epigenetic alterations, telomer...
N. Allehyani, Mohammed Alissa, Abdullah Alghamdi et al.· Reviews in Medical Virology· 0 citations
These findings identify natural-product scaffolds with high potential to modulate UL21-mediated immune suppression, with kaempferol 3,7,4′-tri-O-β-glucoside emerging as the most promising candidate and provide a foundation for experimental validation and future antiviral drug development targeting HSV-1.
Muhammad Suleman, Imtiaz Ali, A. M. Sayaf et al.· PLoS ONE· 0 citations
The human monoclonal antibody MR191N provides complete post-exposure protection in non-human primates and necessitates adaptive trial designs, expanded diagnostic models, and synergistic combination therapies to address MVD.
V. Kandi, F. Branda, Mohammed Alissa et al.· Expert Review of Anti-Infect...· 0 citations
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