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Mohammed Alissa

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Open access Sep 2026

Global, regional, and national burden of tetanus in 204 countries and territories, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023

Summary Background Tetanus is a life-threatening, vaccine-preventable disease. Its incidence decreased substantially following global initiatives such as the Expanded Programme on Immunization (EPI) and Maternal and Neonatal Tetanus Elimination (MNTE). Despite these efforts, tetanus elimination has not been achieved, a...

D. Areda, Hyunjee Kim, Ji-Seung Kang et al. · 0 citations
Review Open access Sep 2026

CRISPR-Engineered CAR-T Cell Therapy for Epstein-Barr Virus-Associated Nasopharyngeal Carcinoma: A Review of Emerging Therapeutic Prospects.

Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC) remains a clinically challenging malignancy, particularly in recurrent or metastatic disease where durable responses to chemoradiotherapy and immune checkpoint blockade are limited. The viral aetiology of NPC provides a strong biological rationale for i...

N. Allehyani, Mohammed Alissa, Abdullah Alghamdi et al. · 0 citations
Aug 2026

Bioactive Streptomyces-Derived Silver Nanoparticles Enhance Antibacterial Activity against Cephalosporin-Resistant Escherichia coli and Klebsiella through Membrane Disruption and In Vivo Efficacy.

Cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae increasingly limit therapeutic options, necessitating novel antimicrobial strategies. This study investigated the antibacterial and immunomodulatory potential of a bioactive Streptomyces isolate (SGM-12) and its silver nanoparticle (AgNP) formulations u...

Mohammed Alissa · 0 citations
Review Open access Aug 2026

Oncoviruses at the Crossroads of Ageing and Cancer: Molecular Mechanisms and Key Signalling Pathways.

Oncoviruses are responsible for a substantial fraction of human cancers and have emerged as critical modulators of host cellular pathways that also govern ageing. The convergence of viral oncogenesis, ageing, and cancer reflects shared molecular mechanisms, including genomic instability, epigenetic alterations, telomer...

N. Allehyani, Mohammed Alissa, Abdullah Alghamdi et al. · 0 citations
Open access Sep 2026

Mechanistic inhibition of herpes simplex virus-1 UL21 immune-evasion function by natural-product scaffolds: A multi-tier docking, dynamics, and energetic profiling approach

These findings identify natural-product scaffolds with high potential to modulate UL21-mediated immune suppression, with kaempferol 3,7,4′-tri-O-β-glucoside emerging as the most promising candidate and provide a foundation for experimental validation and future antiviral drug development targeting HSV-1.

Muhammad Suleman, Imtiaz Ali, A. M. Sayaf et al. · 0 citations
Review Open access Aug 2026

Advances in therapeutics and vaccines for Marburg virus disease: challenges and future directions.

The human monoclonal antibody MR191N provides complete post-exposure protection in non-human primates and necessitates adaptive trial designs, expanded diagnostic models, and synergistic combination therapies to address MVD.

V. Kandi, F. Branda, Mohammed Alissa et al. · 0 citations

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