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Author

Mohan Babu

2 papers indexed here

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Open access Aug 2026

Membrane Mimetic-Thermal Proteome Profiling Reveals Broad, Sequence-Independent Membrane Protein Stabilization by Cholesteryl Hemisuccinate

Membrane protein stability is strongly influenced by the surrounding lipid environment, yet how individual lipid species shape membrane proteome stability remains poorly understood. Here, we systematically examined the impact of sphingomyelin, 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), and cholesteryl hemisuccina...

Ashim Bhattacharya, Shamus Clunie, Frank Antony et al. · 0 citations
Open access Aug 2026

A detergent-free workflow for native membrane proteomics using Peptergents

Quantitative membrane proteomics remains fundamentally limited by sample preparation because detergent extraction can perturb membrane protein interactions, ligand-responsive conformations, and higher-order assemblies before mass spectrometric analysis. Here, we demonstrate that peptide-based surfactants (Peptergents)...

Frank Antony, Ashim Bhattacharya, Hiroyuki Aoki et al. · 0 citations

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