Review
Open access
Sep 2026
Exosomes and the NLRP3 Inflammasome: A Bidirectional Axis in Cellular Signaling and Vesicle Trafficking in Health and Disease
Exosomes are small extracellular vesicles (EVs) generated through the endosomal pathway that mediate intercellular communication by transferring proteins, lipids, and regulatory RNAs. In parallel, the NLRP3 inflammasome is a key signaling platform of the innate immune system that integrates cellular stress signals to d...
R. Franzin, Luigi Malaspina, A. Storelli et al.
· Biologics · 0 citations