Author

Monica M. Sousa

2 papers indexed here

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Open access Sep 2026

In vitro programming and pseudounipolarization of human iPSC-derived sensory neurons

Ectopic expression of NGN1, BRN3A and ISLET1 (NBI) from a safe harbor locus in induced pluripotent stem cells (iPSCs) yielded robust differentiation into functional sensory neurons (iNBI-SNs) within seven days. Single nucleus transcriptomics identified peripheral sensory neuron profiles of nociceptors and mechanorecept...

Pascal Röderer, A. C. Costa, M. Lürkens et al. · bioRxiv · 0 citations

Review Open access Jul 2026

Curving Actin Across Systems: Do Axonal Actin Rings Share Common Underlying Mechanisms?

Actin polymerization into curved and ring‐shaped structures is an evolutionarily conserved mechanism that cells use to generate force, transmit tension, and maintain membrane architecture. In neurons, super‐resolution imaging has revealed a striking periodic submembranous scaffold in axons, composed of circumferential...

A. R. Costa, Luís P. Rodrigues, Monica M. Sousa · Journal of Neurochemistry · 0 citations