Open access
Sep 2026
Recursive feedback between Piezo1 conformation and membrane mechanics drives self-organization into finite clusters
Overall, these results recast Piezo1 mechanotransduction from isolated-channel force sensing to a membrane-driven self-organization process that spatially biases force-dependent calcium signaling within cells.
Zi-Xian Guo, Amrit Bagchi, Monika Dhankhar et al.
· bioRxiv · 0 citations