Motojiro Yoshihara

Calcium sensing by the C2A domain of Synaptotagmin 7 is required through the linker for both synaptic facilitation and memory.

The earliest synaptic plasticity, called synaptic facilitation, is frequently observed at the beginning of any train of action potentials carrying information in the brain. During consecutive action potentials with short intervals, transmissions influence later ones, often enhancing neurotransmitter release. Facilitati...