Mechanism-aware and safety-validated AI for drug repurposing: a critical review and translational pharmacology framework
This critical review summarizes existing AI approaches to drug repurposing, identifies their mechanistic, safety, and translational barriers, and incorporates the emerging evidence gaps into a mechanism-driven and safety-proven translational pharmacology model.
Moumita Hazra, Harishchander Anandaram
· Frontiers in Pharmacology · 0 citations