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Author

Muhammad Junaid

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Review Open access Sep 2026

Next-generation CAR-T cell therapy against cancer: precision engineering, programmable immunity, and emerging clinical frontiers

While chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment of hematological malignancies, there are significant hurdles to overcome, such as antigen escape, T-cell exhaustion, limited persistence in the body, severe toxicities, manufacturing complexity, high costs, and low effectiveness in...

Faizan-e-Mustaffa, Muhammad Shahbaz Aslam, Muhammad Junaid · 0 citations

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