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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Munila Tuersun

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Open access Sep 2026

NRF2 activation attenuates obesity-induced adipose inflammation by suppressing STING signaling, with depot-specific regulation

Obesity-induced oxidative stress triggers the cGAS-STING pathway via mitochondrial DNA (mtDNA) leakage, driving chronic white adipose tissue (WAT) inflammation. Nuclear factor erythroid 2-related factor 2 (NRF2) is a master transcriptional regulator of antioxidant responses, but whether it can serve as an endogenous ne...

Yu-Dong Xia, Xiao-Ying Zhai, Lin-Cong Zhao et al. · 0 citations

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