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Author

Murim Choi

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Open access Sep 2026

A refined MASH–HCC model identifies macrophage Gadd45b as a key orchestrator of inflammation-driven neoplastic progression

Metabolic dysfunction-associated steatohepatitis (MASH) is emerging as a leading driver of hepatocellular carcinoma (HCC), yet the molecular mechanisms linking metabolic stress, chronic inflammation and tumorigenesis remain poorly understood. Here we established a metabolically relevant, time-efficient MASH-to-HCC mode...

Hyunmi Kim, Gye-Hyeong Kim, H. Yeon et al. · 0 citations
Open access Jan 2026

Identification of Novel Pathogenic Variants in Familial Adenomatous Polyposis Through Whole Genome Sequencing

It is demonstrated that cryptic pathogenic APC variants beyond the detection limits of routine genetic testing can be resolved through WGS combined with transcript‐level validation, highlighting the importance of transcript‐aware variant interpretation and supports the integration of genome‐wide sequencing and RNA‐base...

Sung-Ryung Choi, Min Jung Kim, Ja-Lok Ku et al. · 0 citations

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