Open access
Jul 2026
Integrative structure determination of a human mitochondrial contact site and cristae organizing system (MICOS) sub-assembly
The results indicate that Mic13 likely facilitates MICOS assembly by binding Mic10 in the IMM-proximal region and Mic60 in the intermembrane space, and several likely-pathogenic missense mutations also localize to these novel interfaces, highlighting their importance.
Muskaan Jindal, Rakesh Mahato, Sreemoyee Das et al.
· bioRxiv · 0 citations