Aug 2026
Phenothiazine-tetrazole hybrids as potent cholinesterase inhibitors: Integrated experimental and computational insights for Alzheimer's therapy.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by neuronal loss and cognitive decline. A key pathological feature of AD is the reduction of acetylcholine (ACh) levels resulting from the enzymatic activity of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Therefore, inh...
A. Dişli, Bensu Tan, Ş. Adem et al.
· Bioorganic chemistry (Print) · 0 citations