Author

N. Al‐Hoshani

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Oct 2026

Integrating in vitro and in silico correlation of thiazole-based carboxamide derivatives as promising SARS-CoV-2 papain-like protease inhibitors: a versatile approach for COVID-19 therapy

Abstract A new series of thiazole-based carboxamide derivatives (5–12) was designed, synthesized with structural elucidation performed using standard spectroscopic techniques including NMR and HRMS. The synthesized compounds were evaluated for their inhibitory activity against SARS-CoV-2 papain-like protease (PLpro) an...

Imran Khan, Rafaqat Hussain, Hina Sarfraz et al. · Zeitschrift für Naturforschu... · 0 citations

Review Aug 2026

Lysosomal Rewiring Perpetuates Tumor Immune Evasion in Cancer

A conceptual framework linking metabolic, oxidative, oncogenic, and inflammatory pressures to six dominant lysosomal rewiring programs is proposed, offering a mechanistic and translational roadmap for developing lysosome‐directed strategies to restore anti‐tumor immunity.

N. Al-Hoshani, Asad Ullah, M. Ali et al. · Immunology and Cell Biology · 0 citations

Open access Aug 2026

Structure-Guided Immunoinformatics for the Rational Design of a Multi-Epitope Vaccine Against Batai Orthobunyavirus

This study presents a structurally optimized and validated multiepitope vaccine candidate against the emerging Batai orthobunyavirus, identifying a promising vaccine candidate for further investigation; however, its immunogenicity, safety, and protective efficacy before further vaccine development can be considered.

M. A. Alwaili, N. Al‐Hoshani, Huda A Alqahtani et al. · Pharmaceuticals · 0 citations