Author

N. Amodio

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Review Open access Aug 2026

Bispecific Antibodies for Acute Myeloid Leukemia: From Bone Marrow Immune Niche to Clinical Translation

The biological rationale for immunotherapy in AML is summarized, with a focus on the role of the BM microenvironment and immune dysregulation, and the structural and functional properties of IgG-like and non-IgG-like bsAbs and key antigenic targets under clinical investigation are discussed.

A. Bruzzese, E. Martino, Santino Caserta et al. · Antibodies · 0 citations

Review Open access Sep 2026

Mitochondrial Fitness as a Functional Immune Checkpoint in Cancer: Metabolic Plasticity, Tumor Evolution, and Immunotherapy

Integrating functional mitochondrial profiling into precision oncology can optimize biomarker development, clarify resistance mechanisms, and improve the durability of immunotherapy responses.

F. Morabito, E. Martino, A. Bruzzese et al. · Cancers · 0 citations