Author

N. Andelová

2 papers indexed here

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Open access Sep 2026

Proteomic Signatures of Cardiac Mitochondrial Remodelling During Acute Diabetes Reflect Metabolic and Redox Adaptations.

BACKGROUND Mitochondria play a central role in cardiac energy metabolism and dynamically adapt to changes in metabolic demand. However, the early mitochondrial adaptations accompanying the acute phase of diabetes mellitus remain insufficiently understood. This study aimed to characterise diabetes-induced mitochondrial...

N. Andelová, D. Janko, M. Zvarík et al. · Frontiers in Bioscience · 0 citations

Open access Jul 2026

SGLT2i attenuates biventricular remodeling and preserves connexin 43 in experimental volume-overload heart failure

Heart failure (HF) caused by chronic volume overload is associated with progressive structural, electrical, and metabolic remodeling, leading to ventricular dysfunction and increased arrhythmogenic risk. Although sodium–glucose cotransporter-2 inhibitors (SGLT2i) provide significant cardioprotection, their glucose-in...

M. Sýkora, K. Ondreják Andelová, V. Farkašová et al. · Scientific Reports · 0 citations