Open access
Aug 2026
Antibacterial Activity of α‐Sulfamidophosphonate Derivatives and Their In Silico Assessment as Dihydropteroate Synthase Binders
In this study, we report the first antibacterial evaluation of a focused library of 12 previously synthesized α‐sulfamidophosphonate derivatives (4a–4l) against a panel of nine Gram‐positive and Gram‐negative strains, including ESBL‐ and carbapenemase‐producing Enterobacterales. The overall hit rate was modest, as most...
Racha Ghodbane, A. Mairi, H. K'tir et al.
· Chemistry and Biodiversity · 0 citations