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N. Azlina

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Open access Oct 2026

Central composite design process optimization of ultrasound-assisted extraction of phenolic compounds from Manihot esculenta leaves

Cassava (Manihot esculenta) leaves are an underutilized biomass source of phenolic compounds. This study optimized ultrasound-assisted extraction using a central composite design with extraction time and solid-to-liquid ratio as independent variables and total phenolic content (TPC) as the response. Across 13 runs, TPC...

Amiesha Nur Shaheerah Mazlan, N. Azlina, Mohamad Syafiq Abdul Wahab et al. · 0 citations

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