Author

N. Banovich

3 papers indexed here

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Open access Sep 2026

IPF distal lung epithelial cells acquire a DNA methylation signature consistent with activation of basal cell transcriptional programs

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic interstitial lung disease associated with failed alveolar epithelial repair with an expansion of aberrant airway-like epithelium in the alveolar space leading to lung function decline usually resulting in death within 3-5 years of diagnosis. While single-cel...

A. Colvard, Stefano A. Iantorno, I. P. Gaona et al. · bioRxiv · 0 citations

Open access Sep 2026

Multiomic analysis identifies T cell subsets and mechanisms of epithelial interaction in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized by progressive scarring and respiratory failure. While T cells are elevated in IPF lungs, their contributions to fibrosis beyond inflammation remain poorly understood. Here, we performed multiplex imaging and single-cell RNA and prot...

A. Serezani, Julia M. R. Bazzano, B. Pascoalino et al. · JCI Insight · 0 citations

Open access Aug 2026

Inflammatory Fibroblasts Promote Repair After Injury Through Epithelial Proliferation

By integrating several robust murine lung injury data sets, this work establishes the persistence of the inflammatory fibroblast across multiple injury models and identifies a role for these cells in lung repair after injury through effects on alveolar epithelial proliferation.

Luis R. Rodríguez, Willy Roque Barboza, A. Murthy et al. · bioRxiv · 0 citations