Author

N. Beschorner

2 papers indexed here

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Sep 2026

Development of a Recombinant Adeno-Associated Virus Vector for Human T Lymphocyte- and Natural Killer Cell-Targeted Gene Therapy.

Recombinant adeno-associated virus (rAAV) vectors are widely used for gene delivery but show limited efficiency in immune cells, including T lymphocytes and natural killer (NK) cells. To overcome this barrier, we have developed a CD7-targeted rAAV vector (CD7-AAV6/9) featuring a nanobody-fused hybrid capsid derived fro...

H. Jahnz, M. V. Hamann, Hongil Kim et al. · Human Gene Therapy · 0 citations

Open access Aug 2026

Development of an investigational medicinal stem cell gene therapy product to attempt curing human immunodeficiency virus infection

For most people living with Human immunodeficiency virus (HIV), virus control and sufficient immune function can be achieved with polypharmacotherapy. A minority is intolerant to thereto, and drug-resistant mutants are emerging. Additionally, people living with HIV (PLWH) have significantly higher risk of cardiovascula...

Laura Weigand, S. Herkt, Maike Voges et al. · Scientific Reports · 0 citations