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Author

N. Beyhoff

2 papers indexed here

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Open access Aug 2026

Myeloid cell expansion propels right ventricular dysfunction in HFpEF via sterile inflammation

Background Leukocyte’s role in frequently occurring right ventricular dysfunction (RVD) secondary to HFpEF remains poorly defined, partially due to the lack of suitable small animal models. Here, we followed a translational research approach by establishing a murine HFpEF model developing manifest RVD and analyzed huma...

L. Jaeschke, C. Koçana, A. M. Chitroceanu et al. · 0 citations
Open access Jul 2026

Unmasking Supervillin: SVIL haploinsufficiency causes hypertrophic cardiomyopathy by impairing mechanotransduction and cellular energetics

SVIL-associated cardiomyopathy is established as a mechanistically distinct form of HCM and drugs targeting mitochondrial bioenergetics may be a therapeutic strategy in patients with SVIL-associated cardiomyopathy.

Yifan J. Li, Y. Psaras, V. Steeples et al. · 0 citations

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