Open access
Jul 2026
Protein kinase F regulates the virulence of Mycobacterium tuberculosis
The data suggest that expression of PknF, as a modulator of multiple downstream effector proteins, restricts the virulence of Mtb in the lungs of mice through an NLRP3 inflammasome-independent mechanism, but potentially via suppressing production of the virulence lipid, PDIM.
Flor Torres-Juárez, Shivangi Rastogi, David C. Young et al.
· Infection and Immunity · 0 citations