N. Elsherbiny

VASP attenuates lipopolysaccharide-induced renal injury via modulation of TLR4 signaling, inflammation and oxidative stress.

BACKGROUND Vasopressin (VASP), also known as antidiuretic hormone, is a peptide hormone that helps regulate water balance and vascular tone. Emerging evidence suggests it also modulates immune responses and circulatory dynamics. Lipopolysaccharide (LPS) is found in the cell membranes of Gram-negative bacteria. It activ...

Nanovesicular Spanlastics Thermosensitive Gel for the Ocular Delivery of Voriconazole: Development, Ex Vivo Transcorneal Permeability, and In Vivo Evaluation in a Rabbit Model of Fungal Keratitis

Fungal keratitis remains a leading cause of corneal blindness and eye loss worldwide. Conventional antifungal preparations such as those of voriconazole (VCZ) are often limited by rapid precorneal drug loss and poor corneal penetration, leading to suboptimal therapeutic outcomes. This study aimed to address these limit...

Diacerein Protects Against Obesity-Related Cardiovascular Injury: Evidence from In Silico and In Vivo Studies.