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Author

N. Geoghegan

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Open access Sep 2026

napari-lattice: A user-friendly image processing tool for lattice light-sheet microscopy data.

Lattice light-sheet microscopy (LLSM) has revolutionised live-cell imaging with its ability to resolve sub-cellular detail with high spatiotemporal resolution and minimal phototoxicity. However, LLSM often generates large terabyte-scale datasets that require complex preprocessing, creating bottlenecks in storage, data...

P. Rajasekhar, Michael Milton, N. Geoghegan et al. · 0 citations
Open access Sep 2026

SMCHD1’s DNA binding activity enables its stable retention on chromatin

Chromatin proteins play critical roles in gene regulation, yet frequently we do not fully understand how weak DNA binding affinity of such proteins contributes to their locus-specific actions. Here, we studied SMCHD1, a non-canonical SMC-family protein involved in three-dimensional genome organization and gene repressi...

Rui-Feng Hu, Julissa J. Sánchez-Velásquez, Jieqiong Lou et al. · 0 citations

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