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Open access Sep 2026

Molecular basis of nick ligation in the nucleosome by DNA Ligase IIIα

Genomic DNA is packaged into chromatin through a fundamental repeating unit known as the nucleosome core particle. Chromatinized genomic DNA is constantly exposed to endogenous and exogenous stresses that result in DNA damage, which must be repaired to maintain genome stability. Single-strand breaks (SSBs) are a preval...

Daniel J. Boesch, Nadia I. Martin, Chantal A. Kontor et al. · 0 citations

Longitudinal Risk Prediction in Mammography with Privileged History Distillation

SEM-HD consistently improves long-horizon AUC and pAUC over longitudinal models evaluated without history, particularly in the clinically relevant low false-positive-rate region and recovers much of the performance gap with respect to full-history inference across datasets and backbones.

Banafsheh Karimian, Alexis Guichemerre, Soufiane Belharbi et al. · 0 citations

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