N. Gregg

Moving beyond spike detection: High frequency-driven masking improves seizure onset zone localization in intracranial electroencephalography.

OBJECTIVE Interictal epileptiform spikes (IESs) are widely used biomarkers of epileptogenic tissue in presurgical epilepsy evaluation. However, their reliability for seizure onset zone (SOZ) localization in high-density intracranial electroencephalography (iEEG) remains inconsistent. It is underexplored whether this va...

Electrical perturbation reveals a directional architecture for communication across human visual streams

Invasive network neuromodulation for insular epilepsy: A three-center retrospective study.

This study expands the limited literature on insular neuromodulation by demonstrating effectiveness of RNS and CSS, suggesting potential benefit from combined thalamocortical targeting, and defining parasagittal trajectories as a surgical approach for optimal lead proximity.

Pulvinar and anterior nucleus of the thalamus dual-network neuromodulation for complex epilepsies.

Combined four-lead ANT/PUL DBS appears safe and effective for patients with drug-resistant posterior quadrant and temporal lobe epilepsies and dual-network neuromodulation may provide greater flexibility to individually optimize neuromodulation for complex seizure networks.