Review
Open access
Sep 2026
Copper, cuproptosis, and cancer: biology concepts of a novel cell death
Copper is an essential trace element required for mitochondrial respiration, redox regulation, iron metabolism, and cellular signalling, but excessive or mislocalised copper can be cytotoxic. Cuproptosis is a recently identified form of regulated cell death in which copper binds to lipoylated mitochondrial proteins, pr...
R. Eshraghi, N. Hosseini, Mohammad Sepehr Yazdani et al.
· Apoptosis · 0 citations