Open access
Oct 2026
Whole-exome sequencing identifies a missense variant in the cytoskeletal gene SVIL implicating actin remodeling in COVID-19 severity in a Pakistani cohort
Background The current study investigated host genetic associations with disease severity in COVID-19 patients of South Asian origin and explored its molecular basis. Methods Covid-19 patients were stratified into disease severity groups based on the clinical and radiographic findings. Genomic DNA was extracted from pe...
Madeeha Sadiq, Bushra Wasim, A. Khatoon et al.
· PLoS ONE · 0 citations