Author

N. Kanarek

2 papers indexed here

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Open access Sep 2026

A noncanonical function of the tyrosine degradation enzyme FAH drives CDK4/6 inhibitor resistance in breast cancer

Resistance to standard-of-care therapies remains a major clinical challenge in the treatment of the most common breast cancer, the hormone receptor–positive (HR+) subtype. Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors improve outcomes in early-stage HR+ disease, yet many patients relapse. Resistance mechanisms of rel...

Jenny M. Hogstrom, Hanna M. Doh, A. Kump et al. · Science Advances · 0 citations

Open access Aug 2026

Virus reactivation in acute and long COVID-19

Chronic viral infections are ubiquitous in humans, with individuals carrying multiple viruses that can reactivate during physiological stress, including severe illness1. Notably, SARS-CoV-2 infection has been shown to reactivate chronic viruses such as Epstein–Barr virus and cytomegalovirus, yet the full extent, tempor...

Cole P. Maguire, Jing Chen, Nadine Rouphael et al. · Nature · 3 citations