Author

Niall J. Lennon

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Open access Oct 2026

Generalizability of proteomic risk prediction across biobanks reveals dependence on phenotype definitions

Advances in high-throughput proteomics technologies have enabled the assessment of dynamic health states across biobank-scale cohorts. Disease prediction models built on these data have higher accuracy than baseline clinical models for a broad range of diseases, and provide avenues to understand disease pathogenesis. H...

S. Parsa, Y. Jee, M. Argentieri et al. · medRxiv · 0 citations

Open access Jul 2026

Scalable single-cell isoform profiling with sequencing-by-expansion

This work establishes SBX and the AXELIOS 1 as a transformative platform for high-scale single-cell isoform sequencing and demonstrates that this consensus approach successfully captures the vast isoform diversity of single-cell libraries and enables the accurate measure of differential isoform expression across distin...

Christophe H. Georgescu, Ghamdan Al-Eryani, Allison Brookhart et al. · bioRxiv · 0 citations