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Author

N. Naveen

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3 papers indexed here

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Oct 2026

Design and optimization of HME-based floating dolutegravir extrudates with enhanced drug release and potent anti-viral activity.

The hot-melt extrusion (HME) technique is quite successful in improving the solubility and bioavailability of poorly water-soluble drugs. Herein, we report the development of optimized dolutegravir floating systems prepared by the HME technique using Design-Expert software. Optimized parameters for floating extrudate i...

Manisha S. Jain, Akash G. R., B. Gowthami et al. · 0 citations
Review Aug 2026

From Quantification to Translation: Advanced Bioanalytical Strategies for Evaluating Targeted Drug Delivery Systems Across Molecular, Cellular, and In Vivo Scales.

Emerging approaches like artificial intelligence-enabled bioanalysis, multi-omics, smart biosensing, personalized assessment, and digital twin technology are analyzed as possible remedies to tackle the existing challenges of next-generation targeted drug delivery systems.

B. Gowthami, H. S., Sania Hermain et al. · 0 citations

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