Ethanol Extract of Cyclea barbata Miers Exhibited A Favorable Safety Profile at Moderate Doses in Wistar Rats
BACKGROUND: Cyclea barbata Miers has been identified as a phytoestrogenic candidate with comparable estrogen receptors (ER)α binding activity with 17β estradiol. Though phytoestrogens are reported to modulate reproductive and hormonal physiology, but no systematic in vivo toxicological evaluation of C. barbata extract...