N. Oskina

Spectrum of variants in the filaggrin gene in the Russian population and in patients with ichthyosis vulgaris

Background. The filaggrin protein, encoded by the FLG gene, is key to maintaining a healthy skin barrier and normal immune system function. Filaggrin loss-of-function mutations are the primary cause of ichthyosis vulgaris, a common dermatological disorder. At the same time, high variability in individual variant freque...