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Review Open access Sep 2026

Antibiotic Resistance and the Return to a Pre-Antibiotic Era: A Critical Narrative Review of a Global Catastrophe

Antimicrobial resistance is a growing global crisis that threatens to return humanity to a pre-antibiotic era where common infections become deadly. This narrative review synthesizes evidence from 2000 to early 2026, including Global Research on Antimicrobial Resistance data and World Health Organization surveillance,...

Shaurya Prakash, Saloni Saini, Mahima Bharti et al. · 0 citations
Review Open access Aug 2026

Farnesol as a Multifunctional Regulator of Fungal Biology: Mechanisms and Significance

Farnesol is a small isoprenoid metabolite that has emerged as a key regulator of fungal biology beyond its original identification as a quorum-sensing molecule in Candida albicans. This review examines farnesol across pathogenic and non-pathogenic fungi, emphasizing its roles in morphogenesis, biofilm development, stre...

Shaurya Prakash, N. Rai, Sandhya Shukla et al. · 0 citations
Open access Sep 2026

Excessive EFHD1-dependent ER-mitochondrial contacts drive a maladaptive antiviral response in metabolic liver disease.

Metabolic-associated steatohepatitis (MASH) involves hepatocyte damage that cannot be explained solely by lipid accumulation. Here, to discover injury-specific pathways, we focused on a gene of uncertain function, EF-Hand Domain Family Member D1 (EFHD1), identified in human genome-wide association studies of liver inju...

D. Eberhardt, Emma C. Rekate, Yasmin B. Masini et al. · 0 citations

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