Author

N. Rajab

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Open access Sep 2026

Development and validation of RP-HPLC for the Determination of Caspofungin in the Ufasomes Dispersion, Gel and Rat Plasma

Caspofungin is a lipopeptide echinocandin antifungal and its mechanism involves inhibition of (1,3)-β-D-glucan synthase, disrupting fungal cell wall integrity. This study presents a validated RP-HPLC method for detecting and quantifying CSP in ufasomes dispersion and rat plasma, providing a reliable and reproducible ap...

Sumayah Al-Mahmood, N. Rajab · Iraqi Journal of Pharmaceuti... · 0 citations

Aug 2026

Development of Lyophilized Ebastine-Loaded Novasome Tablets: Comprehensive Physicochemical Characterization and In Vitro/In Vivo Release Evaluation.

INTRODUCTION/OBJECTIVE Ebastine, a second-generation H1 antihistamine, exhibits poor aqueous solubility and consequently low oral bioavailability, limiting its clinical therapeutic efficacy. Novasome is an advanced vesicular nanocarrier system that offers a promising approach to enhance the solubility and dissolution b...

Salam ShantaTaher, Hussein J. Alhazza, H. Alkufi et al. · Recent Advances in Drug Deli... · 0 citations

Open access Sep 2026

Development and Validation of HPLC Method For Quantitative and Qualitative Analysisof Asenapine Maleate from Polymeric Micelles

The precise and confirmed HPLC technique has been established to quantify Asenapine maleate (ASPM) concentration in polymeric micelles. The separation was performed using a C18 analytical column with a mobile phase comprised of acetonitrile: water with 0.2% TFA 50:50 v/v. Flow rate of mobile phase was 1 mL/min, with...

Z. Jassim, N. Rajab, H. A. Javar · Iraqi Journal of Pharmaceuti... · 0 citations