Author

N. S. Handayani

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Open access Oct 2026

Identification and structural characterization of F8 gene variants in Indonesian patients with nonsevere hemophilia A: Evidence from targeted next generation sequencing and in silico analyses

Hemophilia A is a rare genetic disorder caused by deficiency of coagulation factor VIII resulting from pathogenic variants in the F8 gene. The aim of this study was to identify potential pathogenic variants using targeted next generation sequencing (NGS), followed by in silico structural and pathogenicity analyses. Gen...

N. S. Handayani, S. Suprianto, Ni Gagc Kirana et al. · Narra X · 0 citations

Open access Sep 2026

Thalassemia Screening Based on Hematological Data Using Random Forest and Support Vector Machine Models: A Preliminary Study

Thalassemia is a hereditary blood disorder caused by impaired globin chain synthesis and represents a public health concern due to increasing incidence and mortality. Screening comprises three levels: hematological examination (Level 1), hemoglobin analysis (Level 2), and molecular genetic testing (Level 3). When Level...

M. Mardiah, Azhari, Rarastoeti Pratiwi et al. · Science & Technology Asi... · 0 citations