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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

N. Schindler

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Open access Sep 2026

8 Single Cell Transcriptomic Investigation of Renal Cell Carcinoma (RCC) Reveals Tissue Resident Memory Exhausted CD8+ T Cell Signature Associated with Resistance to Immune Checkpoint Inhibition (ICI)

Abstract Background The current standard of care for advanced RCC is ICI-based combination therapies. However, most patients with advanced RCC develop disease progression despite ICI treatment, suggesting a lack of durable immune response. Although a lack of T cell infiltration or the presence of non-tumor-reactive “by...

Rishabh Rout, S. Kashima, M. Hugaboom et al. · 0 citations
Open access Sep 2026

50 Tumor–Myeloid Multicellular Programs Reveal ECM-Associated Macrophage Polarization in ccRCC

Abstract Background Clear cell renal cell carcinoma (ccRCC) is characterized by a highly heterogeneous tumor immune microenvironment. However, how tumor-intrinsic programs shape immune cell states remains incompletely understood. We aimed to identify multicellular programs (MCPs) linking tumor and immune compartments a...

Katsuhiro Ito, S. Kashima, Rishabh Rout et al. · 0 citations

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