Synthesis, computational and in vitro anti-tubercular activity studies of thiadiazole-linked pyridazinone derivatives.
Mycobacterium tuberculosis (Mtb) is an infectious bacterium that causes pulmonary tuberculosis (TB). The emergence of drug-resistant Mtb strains necessitates the need for the identification of novel antitubercular agents. In this study, we have repurposed pyridazinone-1,3,4-thiadiazole hybrids for their in-vitro antitu...