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Open access Sep 2026

54. Development of therapeutics for neurodegenerative diseases via CTL1-targeted induction of M1-to-M2 microglial polarization

Abstract Background Microglia are central regulators of neuroinflammation in neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). In these conditions, pathological stimuli including lipopolysaccharide (LPS) and amyloid-β (Aβ) peptides promote a phenotypic switch from neuroprotective...

M. Inazu, T. Okada, E. Muto et al. · 0 citations

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