Author

N. Thio

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Open access Jul 2026

Mapping Functional Tumor Suppressor Networks in Esophageal Adenocarcinoma Using In Vivo CRISPR Screening and Perturb-sequencing

Findings provide a unifying framework for genomic heterogeneity in EAC, uncover underappreciated tumor suppressor pathways, and establish a resource to guide mechanistic and translational studies aimed at improving treatment strategies in this aggressive cancer.

Ebtihal Mustafa, Katherine Papastratos, Ka-Meng Wu et al. · bioRxiv · 0 citations