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Review Open access Oct 2026

Invasive Ductal Carcinoma of the Breast: Molecular Evolution, Immune Escape, and Therapeutic Implications

- Invasive ductal carcinoma (IDC) is the most common histological form of breast cancer and is characterized by marked molecular and immunological heterogeneity. Its progression from ductal carcinoma in situ (DCIS) to invasive disease is accompanied by disruption of the myoepithelial and basement-membrane barriers, ext...

N. Ukibe, C. Onyenekwe, Chidiogor Marigold Iheukwumere et al. · 0 citations
Review Open access Sep 2026

Regulatory T Cells in Immune Homeostasis: Mechanisms of Peripheral Tolerance and Immunoregulation

- Regulatory T cells (Tregs) are specialized subsets of T lymphocytes that maintain immune tolerance, suppress excessive immune responses, and preserve immune homeostasis. These cells are essential for preventing autoimmunity, controlling inflammation, and modulating immune responses during infection, cancer, and trans...

Augustine Chimdindu Igwe, N. Ukibe, Samuel Chukwuemeka Meludu · 0 citations

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