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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

N. Verheyen

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Open access Jul 2026

Spironolactone in the Treatment of Heart Failure with Mildly Reduced or Preserved Ejection Fraction: Design and Baseline Characteristics of the SPIRIT-HF-DZHK08 Trial.

AIMS This report describes the design and baseline characteristics of the SPIRIT-HF trial and compares them with prior heart failure with mildly reduced or preserved ejection fraction (HFpEF/HFmrEF) trials. METHODS AND RESULTS In this multicenter, double-blind, placebo-controlled phase III trial, 730 patients aged ≥5...

D. Zurkan, B. Pieske, J. Petutschnigg et al. · 1 citation

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