Hemophilia A is a rare genetic disorder caused by deficiency of coagulation factor VIII resulting from pathogenic variants in the F8 gene. The aim of this study was to identify potential pathogenic variants using targeted next generation sequencing (NGS), followed by in silico structural and pathogenicity analyses. Gen...
N. S. Handayani, S. Suprianto, Ni Gagc Kirana et al.· Narra X· 0 citations
Actinomycetes are important sources of bioactive compounds with pharmaceutical potential. Kitasatospora sp. TC-ARCL7, isolated from the rhizosphere of Curcuma longa L., has previously shown anticancer activity against the T47D cell line, but its broader biological activities remain unexplored. This study evaluated the...
Aniska Novita Sari, Dini Achnafani, Sari Haryanti et al.· Science and Technology Indon...· 0 citations
Abstract The fruit of Parijoto (Medinilla eximia) is known for its strong antioxidant activity and diverse bioactive compounds, including tannins, flavonoids, and phenolic acids. However, the phytochemical variations and antioxidant properties associated with different plant parts and fruit maturity stages remain large...
N. N. Sa'adah, Y. Purwestri, N. Wijayanti et al.· Brazilian Journal of Biology· 0 citations
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