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Author

N. Zhao

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Sep 2026

Inhibition of CDK9 improves colonic epithelial dysfunction in DSS-induced ulcerative colitis mice by blocking the IL-6/STAT3 signaling pathway.

BACKGROUND Ulcerative colitis (UC) is driven by relentless mucosal inflammation and epithelial barrier compromise. Cyclin-dependent kinase 9 (CDK9) governs transcriptional elongation, yet its therapeutic potential in restoring the intestinal barrier via the STAT3 signaling axis remains underexplored. METHODS The effe...

Wen-Cui Zhao, Yan-Yun Wu, N. Zhao et al. · 0 citations

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