Microbial halogenated natural products (hNPs) hold ecological, agricultural, and biomedical relevance. The hNP-producing potential of an organism can be assessed by the precise prediction of halogenating enzymes, yet detailed annotations of halogenases are often missing from genomic and metagenomic data. We created a m...
Judit Szenei, Ashleigh Burke, Anne Liong et al.· ACS Omega· 0 citations
The new release of BGC Atlas v2 provides taxonomic assignments for nearly all BGCs, harmonized environmental metadata, nested searches across biosynthetic, taxonomic, environmental and geographic properties, and protein-sequence searches against BGC-encoded genes.
Caner Bağcı, Alec Talamas-Tanner, N. Ziemert· bioRxiv· 0 citations
antiSMASH is widely used for biosynthetic gene cluster (BGC) detection and annotation, but its standard workflow is poorly suited to large metagenomic assemblies, where massive contig counts create severe runtime bottlenecks and complicate downstream result exploration. We present metaSMASH, a re-engineered fork of ant...
Caner Bağcı, Kai Blin, N. Ziemert· bioRxiv· 1 citation· ⚡1
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