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N. Ziemert

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Open access Aug 2026

Computational Pipeline Reveals Nature’s Untapped Reservoir of Halogenating Enzymes

Microbial halogenated natural products (hNPs) hold ecological, agricultural, and biomedical relevance. The hNP-producing potential of an organism can be assessed by the precise prediction of halogenating enzymes, yet detailed annotations of halogenases are often missing from genomic and metagenomic data. We created a m...

Judit Szenei, Ashleigh Burke, Anne Liong et al. · 0 citations
Open access Sep 2026

BGC Atlas v2: biosynthetic gene clusters with taxonomic and environmental context at scale

The new release of BGC Atlas v2 provides taxonomic assignments for nearly all BGCs, harmonized environmental metadata, nested searches across biosynthetic, taxonomic, environmental and geographic properties, and protein-sequence searches against BGC-encoded genes.

Caner Bağcı, Alec Talamas-Tanner, N. Ziemert · 0 citations
Open access Jul 2026

metaSMASH: Scalable Biosynthetic Gene Cluster Detection for Large Metagenomic Assemblies

antiSMASH is widely used for biosynthetic gene cluster (BGC) detection and annotation, but its standard workflow is poorly suited to large metagenomic assemblies, where massive contig counts create severe runtime bottlenecks and complicate downstream result exploration. We present metaSMASH, a re-engineered fork of ant...

Caner Bağcı, Kai Blin, N. Ziemert · 1 citation · ⚡1

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