A mitochondria-targeted ratiometric fluorescent probe for visualizing NO generation coupled with mitochondrial pH variations during autophagy.
Autophagy is a vital cytoprotective pathway against oxidative stress, and the regulatory function of reactive oxygen species (ROS) in autophagy has been thoroughly investigated. However, nitric oxide (NO), a representative reactive nitrogen species, exerts dual contradictory effects on autophagy, and the underlying rea...