Gentiopicroside Attenuates Renal Ischemia-Reperfusion Injury through Suppression of JNK/MAPK Signaling.
BACKGROUND Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury (AKI) with significant clinical impact. Gentiopicroside (GPS), a natural secoiridoid glycoside isolated from traditional medicinal plants, has been reported to exert anti-inflammatory and cytoprotective activities, yet its potent...