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p38 MAPK-associated autophagic response restrains TLR4/MyD88 signaling in RT-treated macrophages.
Ricin toxin (RT) is a highly potent plant-derived toxin that causes severe cellular injury and inflammatory responses, yet effective therapeutic interventions remain limited. Autophagy is a conserved stress-response pathway that maintains intracellular homeostasis and modulates innate immune signaling. However, whether...