Review
Open access
Oct 2026
Bile acid signaling in health and disease
Bile acids (BAs), cholesterol-derived amphipathic metabolites which are traditionally regarded as digestive surfactants, are now recognized as pleiotropic signaling molecules that act through ligand-, receptor-, and tissue-specific mechanisms to maintain systemic homeostasis. They exert biological functions via nuclear...
Zhe-Zhe Fan, Meng-Yi He, Tai-Ping Liang et al.
· Molecular Biomedicine · 0 citations