Nagwa M. A. Al-Nagar

Synthesis, DFT, molecular docking, and insecticidal evaluation of new pyrazole-thiazole hydrazones derivatives against Tribolium castaneum.

By reacting ethyl-3-oxo-2-(2-(p bromo)hydrazono)butanoate (1) with various α-halocarbonyl compounds, such as ethyl 2-chloro-3-oxobutanoate 3 and ethyl 2-chloro-2-(aryldiazenyl) acetate 5a-d, this work produces a new series of pyrazole-thiazole derivatives 4 and 6a-e. The target compounds' structures were determined and...